Information for patients taking part in research
We're so grateful to all the East Lancashire patients who’ve volunteered to take part in health research. You join over 35,000 participants since 2008, from our hospitals, who contribute to a better understanding of disease and finding new treatments.
Safety is our priority
The safety of patients and hospital staff is our top priority and we are following the Trust guidance for infection control and hospital appointments. This includes minimising footfall on the hospital site, maintaining social distancing and using decontamination procedures.
If you’re taking part in a research study
If you were taking part in a research study at the hospital before the COVID-19 outbreak, the study team will have contacted you to discuss any changes to your follow up appointments, or to your medication and how to collect this from the hospital. As we restart any research that was temporarily paused, the study team will continue to inform you of any changes that may affect you.
If you have any questions or concerns, please don’t hesitate to get in touch with your study team. Their contact details are as follows:
For women’s health research: 01282 803081
For children's research: 01254 732643
For cancer research: 01254 733299
To find out more about our research
If you’d like to find out more about research at East Lancashire Hospitals, please visit the research pages of this website or you can also follow us on twitter @ELHTresearch. The Be Part of Research website also provides more information on research and lists the studies taking place in East Lancashire and nationally throughout the NHS.
You can find out more about our response to the COVID-19 pandemic here.
For further information about these studies please contact the Research Support Office by calling 01254 732756.
|
Short title |
Description |
Status |
Local Researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
| ISARIC | ISARIC/WHO Coronavirus Clinical Characterisation Protocol for Severe Emerging Infections | Open | Dr S Chukkambotla | Oxford University Hospitals NHS Trust | Study website |
| RECOVERY | Randomised Evaluation of COVID-19 Therapy | Open | Dr Nick Truman | University of Oxford | Study website |
| REMAP-CAP | Randomized, Embedded, Multifactorial, Adaptive Platform trial for Community-Acquired Pneumonia (REMAP-CAP) | Open | Dr Nick Truman | University Medical Center Utrecht | Study website |
| GENOMICC | Genetics of Susceptibility and Mortality in Critical Care Study |
Open | Dr M Smith | University of Edinburgh and NHS Lothian Health Board | Study website |
* Study not open to new participants at ELHT (Temporary pause due to COVID 19)
Last updated 01st June 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Local researcher |
Sponsor |
Further information |
|---|---|---|---|---|
|
PQIP |
Improving perioperative care through the use of quality data: Patient Study of the Perioperative Quality Improvement Programme |
Dr M Pollard |
University College London | |
| VITDALIZE | Effect of High-Dose Vitamin D3 on 28-Day Mortality in Adult Critically Ill Patients with Severe Vitamin D Deficiency The UK arm of an International Multi-Centre, Placebo-Controlled, Phase III Double-Blind trial |
Dr Anton Krige | University of Birmingham | University of Birmingham |
| MOSAICC | Evaluating the clinical and cost-effectiveness of Sodium Bicarbonate administered for critically ill patients with acute kidney injury and metabolic acidosis | Dr Matthew Smith | University Hospitals of Derby and Burton NHS Foundation Triust | |
| IREHAB | Remote Rehab after ICU | Dr Nick Truman | Ulster University | https://warwick.ac.uk/fac/sci/med/research/ctu/trials/irehab/ |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 01st June 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
|
IBD BioResource |
The UK inflammatory bowel disease bioresource: Progressing from genetics to function and clinical translation in Crohn's Disease & Ulcerative Colitis |
Crohn's disease |
Dr J Collum |
Cambridge University Hospital NHS Foundation Trust | |
| NAFLD Bioresource | The NAFLD BioResource, part of the NIHR BioResource – A Research Study to Characterise Novel Clinical and Genetic Phenotypes, and Understand the Natural History of Non-Alcoholic Fatty Liver Disease (NAFLD) | Hepatology | Dr Ioannis Gkikas | University Hospitals Birmingham NHS Foundation Trust | NIHR Bioresource |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 01st June 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of our cancer studies, please contact the cancer research team on 01254 733299.
|
Short title |
Description |
Local researcher |
Sponsor |
Find out more |
|
|---|---|---|---|---|---|
| PATHOS | A Phase II/III trial of risk-stratified, reduced intensity adjuvant treatment in patients undergoing transoral surgery for Human papillomavirus (HPV)-positive oropharyngeal cancer |
Mr K Panayiotis | Velindre University NHS Trust & Cardiff University | Cancer Research UK website | |
| PROTECTOR | Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal | Mr M Willett | Queen Mary University of London | PROTECTOR study webpage | |
|
UKGPC study |
UK Genetic Prostate Cancer Study |
Dr O Parikh |
The Institute of Cancer Research | ||
| POETIC-A | PreOperative Endocrine Therapy for Individualised Care with Abemaciclib | Miss C Yip | The Institute of Cancer Research | The Institute of Cancer Research website | |
| ICI Genetics | Identification of genetic factors that predispose to immune checkpoint inhibitor toxicity | Dr Hassan Shikhrakab | University of Birmingham | ici-genetics@contacts.bham.ac.uk | |
|
|
|||||
| DETECT-ASCEND 2 | Detecting cancers Earlier Through Elective plasma-based CancerSEEK Testing Ascertaining Serial Cancer patients to Enable New Diagnostic II | Dr Ana Ferreira | Exact Sciences Corp. | ||
| ATNEC |
|
Mr Inder Kumar | University Hospitals of Derby and Burton NHS FT | ATNEC | |
| Cyclone3 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Abemaciclib in Combination with Abiraterone plus Prednisone in Men with High-Risk Metastatic Hormone-Sensitive Prostate Cancer | Dr O Parikh | Ely Lilly and Company Ltd -UK | Lilly Trials | |
| TRACC | Tracking mutations in cell free tumour DNA to predict Relapse in Early Colorectal Cancer | Dr K Prasad | The Royal Marsden NHS Foundation Trust | The Royal Marsden NHS Foundation Trust | |
| PETNECK 2 | PETNECK 2: PET-CT guided, symptom-based, patient-initiated surveillance versus clinical follow-up in head and neck cancer | Mr P kyzas | University of Birmingham | University of Birmingham |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 24th July 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
|
* Study not open to new participants at ELHT (Temporary pause) Last updated 19th June 2023 |
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local Researcher |
Sponsor |
Find out more |
||
|---|---|---|---|---|---|---|---|
| iCorMicA | International study of Coronary Microvascular Angina (iCorMicA): a randomised, controlled, multicentre trial and registry | Cardiovascular | Dr Balachandran | NHS Greater Glasgow and Clyde Healthboard | Clinical Trials.gov website | ||
| OPTIMAS | OPtimal TIMing of Anticoagulation after acute ischaemic Stroke: a randomised controlled trial. | Stroke | Dr Singh | University College London | https://optimas.org.uk/ | ||
| AFAR | Atrial Fibrillation After Resection | Cardiovascular | Mr Heywood | Sheffield Teaching Hospital | AFAR | ||
| DNA Lacunar | Genetic risk factors for cerebral small vessal disease | Stroke | Dr Anand Nair | Cambridge University Hospitals | University of Cambridge | ||
| REDUCE | Reducing the impact of diabetic foot ulcers (REDUCE): A effectiveness and cost-effectiveness Randomised Controlled Trial | Diabetes | G Lomax | University Hospitals of Derby & Burton NHS Foundation Trust | Clinical Trials.gov website | ||
| Huawei Stroke Study (HSS) |
|
Stroke | Mark Delabajan |
University of Liverpool | HSS | ||
| RADAR | Rapid Assay Diagnostic for Acute Stroke Recognition | Stroke | Dr Catherine Curley |
Northumbria Healthcare NHS Foundation Trust |
https://www.hra.nhs.uk/planning-and-improving-research/application-summaries/research-summaries/radar-trial/ | ||
* Study not open to new participants at ELHT (Temporary pause)
Last updated 01st September 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| SAVER | Sodium Valproate for Epigenetic Reprogramming in the Management of High Risk Oral Epithelial Dysplasia | Oral and Dental Health | Mr K Panayiotis | University of Liverpool | https://livrepository.liverpool.ac.uk/3130119/ | ||||||
| PHIND | Clinical evaluation of a POC assay to identify PHenotypes IN the Acute Respiratory Distress Syndrome | Respiratory | Dr Waqar-Uddin | Queen's University Belfast | |||||||
| ASPECT | Aspirin after hospitalisation with Pneumonia to prevent cardiovascular Events randomised Controlled Trial | Respiratory | Dr K Geerthan | ||||||||
| TB Dili | Reintroduction of anti-tuberculosis therapy following drug-induced liver injury | Respiratory | Dr Stephen Wilson | Nottingham University Hospitals NHS Trust | https://www.nctu.ac.uk/studies/current-studies/tb-dili.aspx | ||||||
| STARFISH |
|
ENT | Mr S Narayan | University of Birmingham | The Starfish Trial | ||||||
* Study not open to new participants at ELHT (Temporary pause)
Last updated 03rd July 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
|
|
|||||
|
BADBIR |
British Association of Dermatologists Biologic Interventions Register |
Skin |
Dr Owen |
University of Manchester | |
|
B-STOP |
A multicentre, prospective, cohort study to establish clinically relevant pharmacogenetic markers of systemic treatment outcomes in patients with severe psoriasis |
Skin |
Dr Owen |
Guy's and St Thomas' NHS Foundation Trust |
|
| BILAG | BILAG Biologic Prospective Cohort | Musculoskeletal | Prof L S Teh | University of Manchester | |
| Toxicity from biological therapy (BSRBR) | Prospective observational study of the long term hazards of biologic therapy in rheumatoid arthritis. | Musculoskeletal | Prof Symmons | Universuty of Manchester | https://www.bsrbr.org/ |
| IMID Bioresource | IMID (Immune-Mediated Inflammatory Diseases)BioResource - part of NIHR BioResource | Muskoskeletal | Prof L S Teh | University of Manchester | |
| Hand 2 | Hand-2: Needle fasciotomy versus limited fasciectomy for the treatment of Dupuytren’s contractures of the fingers: a randomised, multi-centre non-inferiority trial | Rheumatology | Mr Fizan Younis | Nottingham University Hospitals NHS Trust | The Hand 2 Study |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 01st June 2023
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|
| Panraman | New biomarker identification of pancreatic cancer to improve diagnosis | Mr D Subar | Lancaster University | |
| The Sunflower Study | A randomised controlled trial to establish the clinical and cost effectiveness of expectant management versus pre-operative imaging with Magnetic Resonance Cholangiopancreatography (MRCP) in patients with symptomatic gallstones undergoing laparoscopic cholecystectomy at low or moderate risk of common bile duct stones | Mr D Subar | Leeds Teaching Hospitals NHS Trust | CTEU Bristol website |
| UK-ROX | Evaluating the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care. | Dr N Truman | Intensive Care National Audit & Research Centre | ICNARC website |
| SPECS | A mechanistic trial comparing standard care versus prehabilitation in patients undergoing elective HPB and colorectal cancer surgery: a feasibility study | Dr Joel Lambert | East Lancashire Hospitals NHS Trust | |
| The Orion Trial | Radio Frequency ablation for haemorrhoids (ORION) | Mr Louis Vitone | Sheffield Teaching Hospitals NHS FT | The Orion Trial |
| EVIS | Early Vasopressors in Sepsis | Dr Nick Truman | NHS Greater Glasgow and Clyde Healthboard | https://sepsisresearch.org.uk/evis/ |
| WHITE 11 | The World Hip Trauma Evaluation | Mr Andrew Sloan | University of Oford | https://www.ndorms.ox.ac.uk/research/clinical-trials/current-trials-and-studies/the-white-study |
|
|
* Study not open to new participants at ELHT (Temporary pause)
Last updated 21st June 2023
You may need to talk to your doctor or midwife about taking part in the studies listed here.
If you’re already taking part in a research study and it is not listed here, the study may be closed to recruitment. This means that all the patients that the researchers needed to include, have been entered into the study. However, for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact the women's health research team:
Burnley General Hospital: 01282 803081
Royal Blackburn Hospital: Women's health: 01254 732650; Children's research: 01254 732643.
|
Short title |
Description |
Patient group |
Local Researcher |
Sponsor |
Find out more |
|||
|---|---|---|---|---|---|---|---|---|
|
UK ITP registry |
The UK Paediatric ITP Registry |
Children, |
Dr V Holme |
Royal Manchester Children's Hospital | ||||
| CRAFT | Cerclage after full dilatation caesarean section; an investigation into the role of previous in labour caesarean section in future preterm birth risk and potential management strategies | Reproduction | F Clarke | King's College London | ||||
| LOCI | Letrozole Or Clomifene for Ovulation Induction | Reproduction | Ms Nethra | University of Birmingham | ||||
| Glycopy Bromide | A study to assess utilisation and safety of Glycopyrronium Bromide 1mg/5ml Oral Solution as licensed for symptomatic treatment of severe sialorrhoea in children and adolescents aged 3 years and older with chronic neurological disorders in the UK |
Children | Dr Vanessa Holme | DSRU Education and Research Ltd | ||||
| Tommys Rainbow | The Tommy's National Rainbow Clinic Study | Children | Mr Maher | The University of Manchester | https://www.tommys.org/ | |||
|
ESPRIT 2
|
A multi-centre randomised controlled trial to determine the effectiveness of laparoscopic removal of isolated superficial peritoneal endometriosis for the management of chronic pelvic pain in women: ESPriT2 |
Reproduction | Dr Wittersheim | The University of Edinburgh | https://www.ed.ac.uk/centre-reproductive-health/exppect-endometriosis/research/esprit | |||
| Giant Panda | Pregnancy ANtihypertensive Drugs: which Agent is best? | Reproduction | Dr Davies | University of Birmingham | https://www.birmingham.ac.uk/research/bctu/trials/womens/giantpanda/index.aspx | |||
| FACT4CHILD | Folic Acid Clinical Trial: Follow up of children |
Children |
Heather Collier | Ottawa Hospital, Canada | https://clinicaltrials.gov/ct2/show/NCT03269110 | |||
| REGAL Study | Recurrence of Endometriosis: A randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery(REGAL trial) | Reproduction | Mr Aty | University of Aberdeen | University of Aberdeen | |||
| GBS3 |
|
Reproduction | Dr Justine Nugent | University of Nottingham | https://www.gbs3trial.ac.uk/home.aspx | |||
| iGBS3 | Development of a serocorrelate of protection against invasive Group B Streptococcus disease (iGBS) | Children | Dr Konstantindis | St Georges University of London | https://www.gbsatstgeorges.co.uk/igbs3 | |||
| CRAFFT | CRAFFT – Children’s Radius - Acute Fracture Fixation Trial: A multi-centre prospective randomised non-inferiority trial of surgical reduction versus non-surgical casting for displaced distal radius fractures in children. |
Children | Dr Choudhry | University of Oxford | https://www.ndorms.ox.ac.uk/research/clinical-trials/current-trials-and-studies/crafft | |||
| ABA-Feed | The effectiveness and cost-effectiveness of Assets-based feeding help Before and After birth. | Reproduction | Bev Hammond | University of Birmingham |
|
|||
| FERN | Intervention or expectant management of early onset selective fetal growth restriction in Monochorionic Twim Pregnancy | Reproduction | Mr Martin Maher | University of Liverpool | The Fern Study UoL | |||
| STOPPIT-3 | A Randomised Placebo-Controlled Trial of Antenatal Corticosteroids for Planned Birth in Twins | Reproduction | Dr Justine Nugent | Edinburgh Clinical Trials Unit | The University of Edinburgh | |||
| NEOAMRO | Neonatal Antimicrobial Resistance and Outcomes | Children | Dr Jayanthi Murali | St Georges University of London | NeoAMRO | |||
| POISE |
|
Reproduction | Ms Nethra | University College London | https://poise.ac.uk/home.aspx | |||
| The ELSA Study |
|
Children | Dr Chris Gardner | University of Birmingham | https://www.elsadiabetes.nhs.uk/ | |||
| C-POS Questionnaire | Childrens Palliative Care Outcome scale validation | Children | Dr Vanessa Holme | Kings College London | KCL - CPOS | |||
| STOPPIT M | STOPPIT-M: a mechanism of action of health intervention study | Children | Dr Justine Nugent | University of Edinburgh | https://www.ed.ac.uk/edinburgh-pregnancy-research/current-studies/stoppit3 | |||
| SPIROMAC | Spirometry to manage asthma in children | Children | Dr Dennis Corbett | University of Aberdeen | The SpiroMac Trial | |||
| Diamond | Deep infiltrating endometriosis: management by medical treatment versus early surgery: DIAMOND | Reproduction | Mr Abdel-Aty | University of Aberdeen | https://fundingawards.nihr.ac.uk/award/NIHR130310 |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 22nd August 2023
Clinical research studies happening locally and nationally can be found by searching the following databases:
- Be part of research
- Join dementia research
- Research for the future (for patients with diabetes, heart, lung and kidney disease)