Information for patients taking part in research
We're so grateful to all the East Lancashire patients who’ve volunteered to take part in health research. You join over 35,000 participants since 2008, from our hospitals, who contribute to a better understanding of disease and finding new treatments.
Safety is our priority
The safety of patients and hospital staff is our top priority and we are following the Trust guidance for infection control and hospital appointments. This includes minimising footfall on the hospital site, maintaining social distancing and using decontamination procedures.
If you’re taking part in a research study
If you were taking part in a research study at the hospital before the COVID-19 outbreak, the study team will have contacted you to discuss any changes to your follow up appointments, or to your medication and how to collect this from the hospital. As we restart any research that was temporarily paused, the study team will continue to inform you of any changes that may affect you.
If you have any questions or concerns, please don’t hesitate to get in touch with your study team. Their contact details are as follows:
For women’s health research: 01282 803081
For children's research: 01254 732643
For cancer research: 01254 733299
To find out more about our research
If you’d like to find out more about research at East Lancashire Hospitals, please visit the research pages of this website or you can also follow us on twitter @ELHTresearch. The Be Part of Research website also provides more information on research and lists the studies taking place in East Lancashire and nationally throughout the NHS.
You can find out more about our response to the COVID-19 pandemic here.
For further information about these studies please contact the Research Support Office by calling 01254 732756.
|
Short title |
Description |
Status |
Local Researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
| REMAP-CAP | Randomized, Embedded, Multifactorial, Adaptive Platform trial for Community-Acquired Pneumonia (REMAP-CAP) | Open | Dr Nick Truman | University Medical Center Utrecht | Study website |
| GENOMICC | Genetics of Susceptibility and Mortality in Critical Care Study |
Open | Dr M Smith | University of Edinburgh and NHS Lothian Health Board | Study website |
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
|
IBD BioResource |
The UK inflammatory bowel disease bioresource: Progressing from genetics to function and clinical translation in Crohn's Disease & Ulcerative Colitis |
Crohn's disease |
Dr J Collum |
Cambridge University Hospital NHS Foundation Trust | |
| EVEREST IBD | Endoscopic severity image recognition to advance research and training in Inflammatory Bowel Disease | Gastroenterology | Dr Afifi | Hull University Teaching Hospitals | |
| HRV | Heart Rate Variability as a Predictor of Postoperative Complications - A Feasibility Study | Elective major abdominal surgery | Dr Shu Ng | East Lancashire Hospitals NHS Trust |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Local researcher |
Sponsor |
Further information |
|---|---|---|---|---|
|
PQIP |
Improving perioperative care through the use of quality data: Patient Study of the Perioperative Quality Improvement Programme |
Dr M Pollard |
University College London | |
| VITDALIZE | Effect of High-Dose Vitamin D3 on 28-Day Mortality in Adult Critically Ill Patients with Severe Vitamin D Deficiency The UK arm of an International Multi-Centre, Placebo-Controlled, Phase III Double-Blind trial |
Dr Anton Krige | University of Birmingham | University of Birmingham |
| MOSAICC | Evaluating the clinical and cost-effectiveness of Sodium Bicarbonate administered for critically ill patients with acute kidney injury and metabolic acidosis | Dr Matthew Smith | University Hospitals of Derby and Burton NHS Foundation Triust | |
| IREHAB | Remote Rehab after ICU | Dr Nick Truman | Ulster University | https://warwick.ac.uk/fac/sci/med/research/ctu/trials/irehab/ |
| ABBRUPT | 21/504 Amiodarone vs. beta blockade for new onset atrial fibrillation in adult intentive care. | Dr Nick Truman | University of Birmingham | ABBRUPT |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
| CHARMER | Comprehensive Geriatrician led Medication Review WP4 | Ageing | Dr Nicholas Roberts | University of Leicester | https://charmerstudy.org/ |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of our cancer studies, please contact the cancer research team on 01254 733299.
|
Short title |
Description |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|
|
UKGPC study |
UK Genetic Prostate Cancer Study |
Dr O Parikh |
The Institute of Cancer Research | |
| ICI Genetics | Identification of genetic factors that predispose to immune checkpoint inhibitor toxicity | Dr Robin Portner | University of Birmingham | ici-genetics@contacts.bham.ac.uk |
|
|
||||
| ATNEC | ATNEC–Axillary management in T1‐3N1M0 breast cancer patients with FNA or core biopsy proven nodal metastases at presentation who convert to node negative after NEoadjuvant Chemotherapy | Mr Inder Kumar | University Hospitals of Derby and Burton NHS FT | ATNEC |
| TRACC | Tracking mutations in cell free tumour DNA to predict Relapse in Early Colorectal Cancer | Dr K Prasad | The Royal Marsden NHS Foundation Trust | The Royal Marsden NHS Foundation Trust |
| PETNECK 2 | PETNECK 2: PET-CT guided, symptom-based, patient-initiated surveillance versus clinical follow-up in head and neck cancer | Leandros Vassiliou |
University of Birmingham | University of Birmingham |
| ADAPT-P | Impact of apalutamide in metastatic hormone sensitive prostate cancer patients | Dr Omi Parikh | The Royal Marsdn NHS Foundation Trust | ADAPT-P |
| CVLP | Cancer Vaccine Launchpad CVLP | Dr K Prasad | NHS England | https://www.england.nhs.uk/cancer/nhs-cancer-vaccine-launch-pad/ |
| PRESCORES | Preventing Endometrial Cancer: Utility scores of risk-reducing strategies | Mr Mark Willet | Queen Mary - University of London | PRESCORES |
| BC RECON | Diagnosing Bladder Cancer: Evaluating the role of a urinary biomarker test in the reconfiguration of the haematuria clinic investigations | Mr Pillai | University of Birmingham | BC:RECON |
| ARV471 MetBC w 1prior line (VERITAC 2) | Multicenter, Randomized, Open-label Phase 3 Trial of ARV-471± GnRH analogue vs Investigator’s Treatment Choice ± GnRH analogue in Patients with Estrogen Receptor Positive, HER2Negative Advanced Breast Cancer Whose Disease Progressed After One Prior Endocrine based Treatment for Advanced disease | Dr Martin Hogg | Pfizer | ARV471 |
| HER2 RADICAL | The HER2-RADICAL Study - Response adaptive care plan - Tailoring treatment for HER2 positive early Breast Cancer | Dr Martin Hogg | Institute of Cancer Research | HER2 RADICAL |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
|
Short Title
|
Description | Patient Group | Local Researcher | Sponsor | Find out more |
|---|---|---|---|---|---|
|
ELSA
|
The ELSA Study: EarLy Surveillance for Autoimmune diabetes | Children | Dr Chris Gardner | University of Birmingham | https://www.elsadiabetes.nhs.uk/ |
|
iGBS3
|
Development of a serocorrelate of protection against invasive Group B Streptococcus disease (iGBS) | Children | Dr A Konstantinidis | St Georges | iGBS3 |
|
Spiromac
|
SPIROmetry to Manage Asthma in Children (SPIROMAC) | Children | Dr Dennis Corbett | University of Aberdeen | Spiromac |
| Dolfin | DOLFIN - Developmental Outcomes of Long Term Feed Supplementation in Neonates | Children | Dr R Seethamraju | Newcastle Upon Tyne NHS Trust | https://www.npeu.ox.ac.uk/dolfin |
| BASE | Bicarbonate for Acidosis in very preterm babies: a randomised clinical trial | Children | Dr A Sur | University of Oxford | https://www.npeu.ox.ac.uk/base |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local Researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
| AFAR | Atrial Fibrillation After Resection | Cardiovascular | Mr Nick Heywood | Sheffield Teaching Hospital | AFAR |
| DNA Lacunar | Genetic risk factors for cerebral small vessal disease | Stroke | Dr Anand Nair | Cambridge University Hospitals | University of Cambridge |
| Huawei Stroke Study (HSS) | Evaluation of Huawei Smartwear for Detection of Atrial Fibrillation in a Post-Stroke Population: The Huawei Stroke Study | Stroke | Mark Delabajan |
University of Liverpool | HSS |
| COMMITS | Confirming the Mechanism of Motivational Interviewing Therapy after Stroke: a multi-centre randomised controlled trial | Stroke | Mr Stephen Duberley | UCLAN | Commits |
| E-YUKON | Safety and clinical performance of the Yukon Choice PC, Yukon Chrome PC & Yukon Choice Flex Sirolimus Eluting Bioabsorbable Polymer Stents Systems in Routine Clinical Practice: e-Yukon Global Registry | Cardiovascular | Dr K Balachandran | Kings College Hospitals NHS Trust | |
| ULTRA Long | A Prospective Multi-center Single Arm Trial to Assess the Safety and Effectiveness of Longer Length BioFreedomTM Ultra CoCr Biolimus A9TM Coated Coronary Stents (ULTRA LONG) | Cardiovascular | Professor Scot Garg | Biosensors Europe S.A | |
| ICORMICA | International study of Coronary Microvascular Agina | Cardiovascular | Dr Kanarath Balachandran | NHS Greater Glasgow and Clyde Healthboard | Icormica |
| REDUCE Trial | Bio-psychological Mechanisms of action in Improving Diabetic Foot Ulcer Outcomes | Diabetes | Gill Lomax | University Hospitals of Derby and Burton NHS FT | REDUCE |
| DARE | Individual patient and staff activity on in-patient stroke wards V1 | Stroke | Stephen Duberley | UCLAN |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
| ASPECT | Aspirin after hospitalisation with Pneumonia to prevent cardiovascular Events randomised Controlled Trial | Respiratory | Dr K Geerthan | North Bristol NHS Trust | |
| TB Dili | Reintroduction of anti-tuberculosis therapy following drug-induced liver injury | Respiratory | Dr Stephen Wilson | Nottingham University Hospitals NHS Trust | https://www.nctu.ac.uk/studies/current-studies/tb-dili.aspx |
| STARFISH | A randomised controlled trial of STeroid Administration Routes For Idiopathic Sudden sensorineural Hearing loss | ENT | Dr Surya Narayan | University of Birmingham | The Starfish Study |
| IMPROVE | Improving life quality in chronic obstructive pulmonary disease (COPD) by increasing uptake and completion of pulmonary rehabilitation with lay health workers: a cluster randomised controlled trial | Respiratory | Diane Gaiger | Kings College London | https://improvetrial.co.uk/ |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Patient group |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|---|
|
|
|||||
|
BADBIR |
British Association of Dermatologists Biologic Interventions Register |
Skin |
Dr Owen |
University of Manchester | |
|
B-STOP |
A multicentre, prospective, cohort study to establish clinically relevant pharmacogenetic markers of systemic treatment outcomes in patients with severe psoriasis |
Skin |
Dr Owen |
Guy's and St Thomas' NHS Foundation Trust |
|
| BILAG | BILAG Biologic Prospective Cohort | Musculoskeletal | Prof L S Teh | University of Manchester | |
| Toxicity from biological therapy (BSRBR) | Prospective observational study of the long term hazards of biologic therapy in rheumatoid arthritis. | Musculoskeletal | ProfL S Teh | Universuty of Manchester | https://www.bsrbr.org/ |
| Risk of Falls Interviews | To identify the barriers and facilitators to engaging in exercise, in patients over 60 years who are at risk of falls in Rossendal MSK Physiotherapy Department | Musculoskeletal | Michelle Thirlwall | East Lancashire Hopsitals NHS Trust | |
| PEARLS | ProactivE Against Reactive treatment for Lichen Sclerosus | Dermatology | Dr Caroline Owen | University of Nottingham | https://www.nottingham.ac.uk/pearls/ |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor about taking part in the studies listed here.
If you’re already taking part in a research study but can't see it listed here, the study may be closed to recruitment. All the patients that the researchers needed to include, will have been entered into the study. But for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact our research team on 01254 732651 or 01254 733213.
|
Short title |
Description |
Local researcher |
Sponsor |
Find out more |
|---|---|---|---|---|
| Panraman | New biomarker identification of pancreatic cancer to improve diagnosis | Mr D Subar | Lancaster University | |
| UK-ROX | Evaluating the clinical and cost-effectiveness of a conservative approach to oxygen therapy for invasively ventilated adults in intensive care. | Dr N Truman | Intensive Care National Audit & Research Centre | ICNARC website |
| PROPHER | Patient reported outcomes after parastomal hernie treatment - A prospective international cohort study | Mr Nick Heywood | University of Birmingham |
The Propher Study - HRA Website |
| PLACEMENT | Perineural Local Anaesthetic Catheter after Major Lower Limb Amputation | Mr David Ormesher | Cardiff University | PLACEMENT |
| THRIVE | THRomboprophylaxis in Individuals undergoing superficial endoVEnous treatment (THRIVE): a multi-centre, assessor-blind randomised controlled trial | Mr David Ormesher | Imperial College London | THRIVE |
|
|
*Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
You may need to talk to your doctor or midwife about taking part in the studies listed here.
If you’re already taking part in a research study and it is not listed here, the study may be closed to recruitment. This means that all the patients that the researchers needed to include, have been entered into the study. However, for patients already taking part, study treatment and the collection of research data will continue.
For information about any of these studies, please contact the women's health research team:
Burnley General Hospital: 01282 803081
Royal Blackburn Hospital: Women's health: 01254 732650; Children's research: 01254 732643.
|
Short Title |
Description |
Patient Group |
Local Researcher |
Sponsor |
Find out more |
|
ESPRIT2
|
A multi-centre randomised controlled trial to determine the effectiveness of laparoscopic removal of isolatedsuperficial peritoneal endometriosis for the management of chronic pelvic pain in women: ESPriT2 | Reproduction | Dr Robyn Wittersheim | University of Edinburgh | https://www.ed.ac.uk/centre-reproductive-health/esprit2 |
|
Giant Panda
|
Pregnancy ANtihypertensive Drugs: which Agent is best? | Reproduction | Dr Sarah Davies | University of Birmingham | Giant Panda |
|
POISE
|
Hormone therapy for premature ovarian insufficiency: randomised trial and long-term evaluation | Reproduction | Dr S Nethra | University of Nottingham | https://poise.ac.uk/home.aspx |
|
REGAL
|
Recurrence of Endometriosis: A randomised controlled trial of clinical and cost-effectiveness of Gonadotrophin Releasing Hormone Analogues with add-back hormone replacement therapy versus repeat Laparoscopic surgery(REGAL trial) | Reproduction | Dr M Abdel-Aty | University of Aberdeen | Regal |
|
Tommys National Rainbow Clinic
|
The Tommy's National Rainbow Clinic Study | Reproduction | Mr Martin Maher | Manchester Foundation Trust | TOMMYS |
|
Early vs Late Glucose Monitoring
|
An observational nested multicenter cohort study of early versus late monitoring among pregnant women with a history of gestational diabetes | Reproduction | Sarah Carter | Chelsea and Westminster NHS Trust | EarlyvsLate |
|
OBS UK
|
Clinical and cost-effectiveness of a maternity quality improvement programme to reduce excess bleeding and need for transfusion after childbirth: the Obstetric Bleeding Study UK (OBS UK) Stepped Wedge Cluster Randomised Trial | Reproduction | Dr Sarah Loveridge | University of Cardiff | OBS UK |
|
SNAP 3
|
Open-label randomised controlled trial of enhanced support and nicotine replacement therapy (NRT) offered for preloading, lapse recovery and smoking reduction: impact on smoking in pregnancy | Reproduction | Mrs Bev Hammond | University of Nottingham | SNAP 3 |
| The Tommys Project | A Coordinated antental and tissue data study of pregnancy outcome and related disease | Reproduction | Dr Helen Collier | University of Manchester | Tommys |
| MOLI | Mifepristone Outpatient Labour Induction | Reproduction | Dr Justine Nugent | Chelsea and Westminster Hospital NHS FT | MOLI |
| MINESS 20-28 | Mothers working to prevent early stillbirth study | Reproduction | Dr Lindsey Sellers | Manchester University Hospitals FT | MINESS 20-28 |
| The iHOLDS Trial | High or low dose Syntocinon for induction of labour in nulliparous women | Reproduction | Dr Sarah Loveridge | Birmingham Women and Childrens NHS FT | iHOLDS |
| PIONEER | Prevastatin to prevent preterm Birth | Reproduction | Dr Lindsey Sellers | University Hospitals Bristol and Weston NHS FT | PIONEER |
* Study not open to new participants at ELHT (Temporary pause)
Last updated 16 December 2024
Clinical research studies happening locally and nationally can be found by searching the following databases:
- Be part of research
- Join dementia research
- Research for the future (for patients with diabetes, heart, lung and kidney disease)