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Question 1
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Does East Lancashire Hospitals NHS Trust have any local treatment guidelines/pathways/protocols/algorithms for the treatment of non-small cell lung cancer?
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Yes
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No
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If Yes please provide a copy.
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Depends on the definition of local. ELHT uses the Lancashire and South Cumbria Cancer Alliance (Protocols and algorithms:
Lancashire and South Cumbria Health and Care Partnership :: Lung Chemotherapy Protocols and Algorithms (healthierlsc.co.uk)
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Question 2
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Does East Lancashire Hospitals NHS Trust have protocols for the use of the following targeted drug therapies in the treatment of non-small cell lung cancer?
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Sotorasib (Lumykras)
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Yes
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No
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If yes please see question 3
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Entrectinib (Rozlytrek)
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Yes
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No
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Larotrectinib (Vitrakvi)
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Yes
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No
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Dabrafenib (Tafinlar)
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Yes
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No
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Trametinib (Mekinist)
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Yes
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No
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Capmatinib (Tabrecta)
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Yes
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No
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Tepotinib (Tepmetko)
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Yes
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No
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Bevacizumab (Avastin)
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Yes
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No
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Ramucirumab (Cyramza)
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Yes
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No
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Atezolizumab (Tecentriq)
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Yes
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No
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Durvalumab (Imfinzi)
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Yes
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No
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Cemiplimab- (Libtayo)
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Yes
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No
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Nivolumab (Opdivo)
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Yes
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No
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Pembrolizumab (Keytruda)
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Yes
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No
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Ipilimumab (Yervoy)
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Yes
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No
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Afatinib (Giotrif)
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Yes
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No
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Dacomitinib (Vizimpro)
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Yes
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No
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Erlotinib (Tarceva)
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Yes
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No
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Gefitinib (Iressa)
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Yes
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No
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Osimertinib (Tagrisso)
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Yes
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No
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Amivantamab (Rybrevant)
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Yes
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No
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Mobocertinib (Exkivity)
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Yes
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No
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trastuzumab deruxtecan (Enhertu)
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Yes
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No
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Alectinib (Alecensa)
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Yes
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No
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Brigatinib (Alunbrig)
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Yes
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No
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Ceritinib (Zykadia)
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Yes
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No
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Crizotinib (Xalkori)
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Yes
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No
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Lorlatinib (Lorviqua )
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Yes
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No
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Entrectinib (Rozlytrek)
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Yes
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No
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Pralsetinib (Gavreto)
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Yes
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No
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Selpercatinib (Retsevmo)
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Yes
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No
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Nintedanib (Vargatef®)
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Yes
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No
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All Yes answers are as part of LSCCA
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Question 3
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If a local protocol for the use of Sotorasib (Lumykras) for the treatment of non-small cell lung cancer is available please could a copy be provided?
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Link to Cancer Alliance Protocol: - LSCCA Sotorasib
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Question 4
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Does East Lancashire Hospitals NHS Trust have any local pathways/protocols/guidelines for the use of molecular biomarker testing in diagnosis/treatment of non-small cell lung cancer?
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Yes
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No
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If yes please provide a copy
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There is nothing specific we know about, however most targeted treatments are based on molecular test results.
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Question 5
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Is East Lancashire Hospitals NHS Trust part of a Cancer alliance or network, if so which ones?
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